A disease represents one of the many forms of an inherited progressive retinal atrophy. This form of the disease occurs only at Rough and Smooth Collies. A progressive degeneration of the photoreceptors (rods and plugs) in the eye characterizes the disease. The first changes of a visual impairment appearing as the night blindness occur at the age of six weeks. Clinical signs are increasing and at the age of six or eight months, the dogs with rcd2 defect are functionally blind.
Inheritance: autosomal recessive - read more.
Mutation: Gene RD3
Genetic test: Genetic testing can identify affected or carrier animals at any age. The method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs.
Disease control: read more.
Affected breeds: Rough Collie, Smooth Collie
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling are found here.