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EVG, molekularna diagnostika
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Slovenia



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Description

Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and death of photoreceptor cells. PRA in Basenji (Bas-PRA) is late onset version of PRA as the first signs occur at the age of 5 to 7 years. First signs are visual loss in dim light (night blindness), which gradually progresses to total blindness.

 

Inheritance: autosomal recessive- read more

Mutation: S-antigen (SAG) gene

Genetic test: Disease or carrier can be identified by genetic testing at any age. The PCR method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs.

Disease control: read more

Affected breeds: Basenji

Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

 

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