Neonatal cerebellar ataxia (BNAt, Bandera syndrome) is a disease affecting cerebellum (little brain) in Cotton de Tulear dogs. Clinical signs become apparent as soon as unaffected littermates develop coordinate movements. Affected animals exhibit head tremors and are unable to walk. They scoot around and often fall. Vision is unaffected but animals lack a menace response and exhibit ocular tremors.
Inheritance: autosomal recessive - read more
Mutation: GRM1 gene
Genetic test: Disease or carrier can be identified by genetic testing at any age. The PCR method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs.
Disease control: read more
Affected breeds: Coton de Tulear
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.