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EVG, molekularna diagnostika
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Slovenia



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Description

Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and cell death of photoreceptors. In Sloughi, PRA is inherited in an autosomal recessive manner. It is an early onset disease with some individual variation in age of onset. Disease progression is slow and dogs may or may not become completely blind. 

 

Inheritance: autosomal recessive- read more

Mutation: PDE6B gene

Genetic test: Disease or carrier can be identified by genetic testing at any age. The PCR method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs.

Disease control: read more

Affected breeds: Sloughi

Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

 

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