EVG, molekularna diagnostika
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SI-2000 Maribor  

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Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and cell death of photoreceptors. GR-PRA1 is a late onset disease (usually at 6 - 7 year) with some individual variation in age of onset, and is inherited in an autosomal recessive manner. Until now, three different mutations were found to cause progressive retinal atrophy (PRA) in Golden Retriever breed: PRA-PRCD, GR-PRA1 and GR-PRA2.


Inheritance: autosomal recessive- read more

Mutation: SLC4A3 gene

Genetic test: Disease or carrier can be identified by genetic testing at any age. The PCR method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs.

Disease control: read more

Affected breeds: Golden Retriever

Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.


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