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EVG, molekularna diagnostika
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Slovenia



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Description

Van den Ende-Gupta Syndrome (VDEGS) is a skeletal syndrome causing severe skeletal anomalies that are already evident in puppies. The disorder is characterised by patellar luxation, underbite (shorter upper jaw), dislocated radial head and deviated nasal septum. In one study, 22% of the control population were carriers of the disorder.

 

Inheritance: autosomal recessive- read more

Mutation: SCARF2 gene

Genetic test: Disease or carrier can be identified by genetic testing at any age. The PCR method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs.

Disease control: read more

Affected breeds: Fox Terrier

Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

 

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