May-Hegglin Anomaly (MHA) is a hereditary disorder described in Pugs. It is characterized by abnormal hematologic findings, such as persistent thrombocytopenia, macrothrombocytosis and variably shaped, often fusiform, blue cytoplasmic inclusions in neutrophils.

Inheritance: autosomal recessive - read more

Mutation: MYH9 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.