Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and cell death of photoreceptors. GR-PRA 1 usually appears at the age of 6 and leads to vision loss and blindness. It is inherited in an autosomal recessive manner. To date, 3 different mutations that cause PRA have been discovered in Golden Retriever dogs, namely PRA-PRCD, GR-PRA1 and GR-PRA2, of which GR-PRA1 is responsible for more than 60% of all diagnosed cases of PRA.

Inheritance: autosomal recessive - read more

Mutation:  SLC4A3  gene

Genetic test: The method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. Testing can be done at any age.

Disease control: read more

Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.