Ullrich-like congenital muscular dystrophy is an autosomal recessive disorder, characterized by myofiber degeneration and impaired ability of tissues to regenerate due to defects in the formation of mature collagen-6 protein. The clinical signs occur at around 6 months of age and include progressive, severe weakness, prolonged sleep, muscle atrophy, laxity of distal joints, angular contractures of proximal joints, and decreased range of motion of multiple joints.

Inheritance: autosomal recessive - read more

Mutation: COL6A3 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.