Hereditary footpad hyperkeratosis / Digital hyperkeratosis (HFH)

Hereditary footpad hyperkeratosis (HFH), also known as digital hyperkeratosis, is a monogenic autosomal recessive disease that is known in several dog breeds. The disease is a specific form of an orthokeratotic palmoplantar hyperkeratosis, which leads to thickened and hardened footpads. The pad surface then develops cracks and fissures, which can lead to secondary infections. It can be recognised in juvenile dogs, between 18 and 24 weeks of age, but it is usually not noticed by the owners until the age of 4-5 months. If not treated properly, HFH can lead to pain and lameness in affected dogs.

Inheritance: autosomal recessive - read more

Mutation: FAM83G gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.



52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
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