Digital hyperkeratosis (DH/HFH)

Hereditary footpad hyperkeratosis is a hereditary autosomal recessive disease found in dogs and humans. It is well described in Dogue de Bordeaux. The symptoms appear at 4–5 months of age and include a painful thickening and hardening of the footpads with severe keratinous proliferations and fissures, leading to development of cracks. Those cracks predispose affected dogs to secondary infection, which leads to lameness.

Inheritance: autosomal recessive - read more

Mutation: KRT16 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.



52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
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