Hereditary necrotising myelopathy (HNM)

Hereditary necrotising myelopathy (HNM) is an autosomal recessive inherited neurological disease in dogs, that causes a symmetric bilateral necrotising myelopathy with tissue softening in the ventral and dorsal white matter. It is characterised by progressive ataxia and paralysis in affected dogs. The symptoms start to show in the hind limbs and later progress to tetraparalysis. The clinical signs appear around 3–12 months of age in most dogs and progresses before the age of two years. Affected dogs are commonly euthanized due to deteriorated health conditions within the following months of disease progression.

Inheritance: autosomal recessive - read more

Mutation: IBA75 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.



52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
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