Dental hypomineralization (Raine Syndrome) is a hereditary disease which can be tested with a DNA test.  
Dental hypomineralization in Border Collie is autosomal recessive hereditary disease that causes hypomineralization of teeth, leading to extensive wear, chronic inflammation and tooth loss. The genetic defect is relatively common in Border Collies with approximately 11% of carriers.

Inheritance: autosomal recessive - read more

Mutation: FAM20C gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.