Cone-rod dystrophy 2 (cord2 - PRA)

Cone-rod dystrophy 2 (cord2 – PRA / crd - PRA)is a hereditary disease which can be tested with a DNA test. Most of canine retinal hereitary diseases with known causal mutations are rod-cone degenerations also known as progressive retinal atrophies (PRAs), which are characterized by progressive rod-led photoreceptor degeneration that is followed by cone photoreceptor demise. In contrast, cone-rod dystrophies are characterized by the relatively early loss of cone photoreceptors and relative preservation of rod function. Cone-rod dystrophy 2 (cord2 - PRA) is a retinal disease associated with NPHP4 gene in Wirehaired Dachshund. First clinical signs can be detected already at the age of 5 weeks (reduced cone ERG response). Initial ophtalmoscopic changes are usually diagnosed between the age of 10 months to 3 years.

Inheritance: autosomal recessive - read more

Mutation: NPHP4 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Sale

(-30.0%)

54.00 €

Price:

37.80 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
It appears you are using an older browser we don't support fully! For better and user friendly experience use one of the following internet browsers or update your current browser to the latest version.