Muscular dystrophies are a group of inherited, degenerative disorders characterized by progressive muscular dysfunction. Clinical signs start at a few weeks of age, and lead to severe progressive muscle weakness that causes severe problems including problems with gait and standing. Affected dogs also suffer from joint pain. Affected puppies are usually euthanized at first year of age.
Inheritance: autosomal recessive - read more
Mutation: COL6A1 gene
Genetic test: The method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. Testing can be done at any age.
Disease control: read more
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.