Dystrophie neuro-axonale (NAD) - Berger Americain Miniature

Neuroaxonal dystrophy (NAD) is a slowly progressive neurodegenerative disorder with an autosomal recessive inheritance. It is characterised by the presence of large, swollen axons and tissue changes indicative of neuronal degeneration and secondary gliosis throughout the central nervous system. The symptoms of the affected Miniature American Shepherd dogs occur in young adults and include an abnormal, pacing/ambling gait, characterised by pelvic limb weakness and ataxia. Other symptoms encompass incoordination, scuffing of paws/dragging of digits, kyphosis, abnormal behaviour with excessive anxiety and paraparesis with hindlimb ataxia. Although not fatal, the affected dogs eventually develop more severe disabilities, leading to poor quality of life and lastly euthanasia due to the lack of treatment.

Inheritance: autosomal recessive - read more

Mutation: RNF170 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.



54,00 €

  • Vous pouvez commander un kit d'échantillonnage gratuit.
  • Un seul échantillon est nécessaire pour chaque animal, même si vous commandez plusieurs tests.
  • Nous conservons les échantillons pour vous permettre de commander des tests supplémentaires.
  • Nous proposons l'aide d'experts pour l'interprétation des résultats.
Vous semblez utiliser un navigateur obsolète qui ne supporte pas entièrement notre site ! Pour utiliser ce site de façon simple et agréable, utilisez l'un des navigateurs Internet suivants ou téléchargez la dernière version de votre navigateur actuel.