Goniodysgenesis and glaucoma (GG)is a hereditary disease that can be tested with a DNA test. Goniodysgenesis is a developmental abnormality of the anterior chamber of the eye. It is generally considered to be congenital in dogs and has been associated with developing glaucoma in later years. It is marked by an abnormality in the ligaments that are in the eye. These strings block the openings through which the fluid (called aqueous humor) can drain from the eye. This increases pressure within the eye, damages the ganglion layer of retina and leads to blindness. Symptoms mostly appear in eye change: bloodshot look to the eye, shiny looking outside and cloudy inside, high sensitivity to light, raised third eyebrow, winking spasms, rubbing eyes, keeping eyes closed. The hereditary (this hereditary) disease is painful and can lead to loss of appetite and less activity of the dog.

Inheritance: autosomal recessive - read more

Mutation: OLFML3 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.