Hyposegmentation of granulocytes (HG)

Hyposegmentation of granulocytes (HG) is a benign condition characterized by lack of granulocyte nuclear segmentation. The condition is common in Australian Shepherds and in the past was thought to represent the human homologue of Pelger-Huet Anomaly (PHA), which would result in restrictions on the breeding of affected dogs. Recent study provides evidence that HG in Australian Shepherd Dogs is an autosomal recessive trait without major negative consequences for health. Approximately 15% of dogs are homozygous for the causative mutation. The genetic test can be used to confirm the cause of granulocyte hyposegmentation.

Inheritance: autosomal recessive - read more

Mutation: LMBR1L gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.



52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
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