May-Hegglin Anomaly (MHA) is a hereditary disorder described in Pugs. It is characterized by abnormal hematologic findings, such as persistent thrombocytopenia, macrothrombocytosis and variably shaped, often fusiform, blue cytoplasmic inclusions in neutrophils.
Inheritance: autosomal recessive - read more
Mutation: MYH9 gene
Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.
Disease control: read more
DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.