Nemaline myopathy is a congenital muscle disorder that affects both humans and dogs. The disease is characterized by the presence of rod bodies in the skeletal muscle fibres, non-progressive generalized muscle weakness, exercise intolerance, tremors and hypotonia (decreased muscle tone). The disease is typically first observed when puppies are around 2 months old. At this stage, the puppies can move but have generalized muscle atrophy and tremors leading to exercise intolerance.

Inheritance: autosomal recessive - read more

Mutation: NEB gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.