Neuroaxonal dystrophy (NAD) - Papillon

Neuroaxonal dystrophy (NAD) - Papillon is a hereditary disease which can be tested with a DNA test.Neuroaxonal dystrophy (NAD) is an autosomal-recessive hereditary disease in Papillon and some other breeds. NAD is characterized by neurodegenerative pathology of the central and peripheral nervous system in which swellings (spheroids) develop and accumulate along axons throughout the brain and spinal cord. Affected Papillons show various neurological deficits including gait abnormalities, ataxia, tremor, lack of coordination and various behavioural deficits. NAD in Papillon is juvenile-onset as neurological signs start as early as 6 weeks of age.

Inheritance: autosomal recessive - read more

Mutation: PLA2G6 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.


52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
It appears you are using an older browser we don't support fully! For better and user friendly experience use one of the following internet browsers or update your current browser to the latest version.