Neuronal ceroid lipofuscinosis 10 (NCL 10)

Neuronal ceroid lipofuscinosis 10 (NCL-10)is a hereditary disease which can be tested with a DNA test. Neuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and the accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate everyday muscle activities. With the increased neurodegeneration affected dogs also develop psychological abnormalities and ataxia.

Inheritance: autosomal recessive - read more

Mutation: CTSD gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Sale

(-30.0%)

54.00 €

Price:

37.80 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
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