Neuroaxonal dystrophy (NAD) - Spanish water dog

Neuroaxonal dystrophy (NAD) is a hereditary disease which can be tested with a DNA test. Neuroaxonal dystrophy (NAD) is an autosomal recessive hereditary disease in Spanish water dogs and some other breeds. NAD is characterized by neurodegenerative pathology of the central and peripheral nervous system. Affected Spanish water dogs show various neurological deficits including gait abnormalities, behavioural deficits (dullness, nervousness...) and incontinence alone or in combination with uncontrolled defecation.

Hahn et. al. reported that NAD in Spanish water dogs is juvenile-onset. Neurological signs starting between six and eleven months of age. All affected dogs from the study were euthanized between 12 and 23 months of age. 

Inheritance: autosomal recessive - read more

Mutation: TECPR2 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.


52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
It appears you are using an older browser we don't support fully! For better and user friendly experience use one of the following internet browsers or update your current browser to the latest version.