Primary open angle glaucoma (POAG) is a hereditary eye disease. Glaucomas represent a group of diseases characterized by increased intraocular pressure, which causes retinal and optic disk destruction. Primary open angle glaucoma (POAG) in Basset Fauve de Bretagne or Fawn Brittany Basset is an inherited condition with typically increased eye pressure in both eyes. Affected dogs usually develop symptoms between 4 to 6 years of age. As the pressure in the eye increases, the eyeball increases in size and becomes painful. Symptoms include sudden onset of pain, redness, tearing, squinting and blinking of the eye. If POAG is left untreated, increased pressure in the eye leads to optic nerve damage and gradual loss of vision.

Inheritance: autosomal recessive - read more

Mutation: ADAMTS17 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.