Primary ciliary dyskinesia (PCD) - Alaskan Malamute

Primary ciliary dyskinesia (PCD) is a genetic condition affecting motile cilia. Motile cilia are present in the respiratory tract, reproductive tract, brain and spinal cord. They are required for clearing mucous, infectious agents and inhaled dust from the airways. Clinical signs include fertility problems, chronic bronchitis, situs inversus (in about 50% of dogs), bronchopneumonia, bronchiectasis, hydrocephalus, chronic recurrent infections of the respiratory tract and chronic productive cough. PCD has been described in numerous dog breeds including Alaskan Malamutes. Some Alaskan Malamutes are euthanized due to chronic respiratory infections.

Inheritance: autosomal recessive - read more

Mutation: NME5 gene

Genetic test: The method used forgenetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Price:

52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
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