Progressive retinal atrophy in Basenji (Bas-PRA)is a hereditary disease which can be tested with a DNA test. Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and death of photoreceptor cells. PRA in Basenji (Bas-PRA) is late onset version of PRA as the first signs occur at the age of 5 to 7 years. First signs are visual loss in dim light (night blindness), which gradually progresses to total blindness.
Inheritance: autosomal recessive - read more
Mutation: S-antigen (SAG) gene
Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.
Disease control: read more
DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.