Progressive retinal atrophy (PRA-rcd1A) is a hereditary disease which can be tested with a DNA test. Progressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and cell death of photoreceptors. In Sloughi, PRA is inherited in an autosomal recessive manner. It is an early onset disease with some individual variation in age of onset. Disease progression is slow and dogs may or may not become completely blind.
Inheritance: autosomal recessive - read more
Mutation: PDE6B gene
Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.
Disease control: read more
DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.