Progressive retinal atrophy (PRA-rcd2)is a hereditary disease which can be tested with a DNA test. A disease represents one of the many forms of an inherited progressive retinal atrophy. This form of the disease occurs only IN? Rough and Smooth Collies. A progressive degeneration of the photoreceptors (rods and plugs) in the eye characterizes the disease. The first changes of a visual impairment appearing as the night blindness occur at the age of six weeks. Clinical signs are increasing and at the age of six or eight months, the dogs with rcd2 defect are functionally blind.
Inheritance: autosomal recessive - read more
Mutation: RD3 gene
Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.
Disease control: read more
DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.