Recessive dystrophic epidermolysis bullosa (RDEB) a subtype of epidermolysis bullosa (EB) is an inherited severe skin blistering condition caused by mutations in the gene coding for collagen type VII. Golden retrievers suffer from bullous eruptions inherited in an autosomal-recessive mode, with involvement of the oral and esophageal mucosa, and a generalized tendency of the skin to blister with generation of milium. The formation of erosions and blisters of the upper digestive tract persist, causing growth retardation, while blistering of the skin diminishes from the age of 8 months.
Inheritance: autosomal recessive - read more
Mutation: COL7A1 gene
Genetic test: The method used for testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. Testing can be done at any age.
Disease control: read more
Sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.