Shaking puppy syndrome (SPS) – English Springer Spaniel

Shaking puppy syndrome is an inherited genetic defect that results in delayed myelination of the central nervous system. This disorder is caused by lack of myelin, which is a white substance that surrounds the axon of nerve cells and has important role in functioning of the nervous system. The disease is a rare neurological disorder that affects dogs of certain breeds. The first clinical symptoms are characterized by a severe tremor, which is usually appearing at twelve days of age followed by late onset convulsions and, under natural conditions, an early death by about 3-4 months of age. Clinical signs of affected puppies may also include difficulties with keeping balance, coordinating movements and maintaining balance in space.

Inheritance: X-linked recessive - read more

Mutation: PLP1 gene

Genetic test: The method used forgenetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Price:

52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
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