Spastic ataxia is an autosomal recessive hereditary disorder characterized by widespread central nervous system degeneration, leading to progressive cerebellar ataxia and spasticity combined with peripheral neuropathy. Affected dogs appear normal until 3-5 months of age. The first symptoms occur at around 4 months of age and slowly progress over the next several years. They include clumsiness, uncoordinated behaviour and later on distal muscle wasting, overall weakness and lower limb spasticity. The affected dogs usually have to be euthanised by 4-7 years of age due to progression of the disease.

Inheritance: autosomal recessive - read more

Mutation: SACS gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.