Spinocerebellar ataxia (SCA) – mutation 2

Spinocerebellar ataxia is a progressive neurodegenerative autosomal recessive hereditary disorder characterized by uncoordinated walking, problems with movement or, in some cases, complete loss of ability to move, seizures and myokymia. The affected dogs usually have to be euthanised under the age of 4 years due to worsening of clinical signs.

The symptoms are very similar to signs shown by dogs affected with Late Onset Ataxia (LOA), so there may be a confusion in identification of this hereditary disease.

There are two known mutations in KCNJ10 gene associated with spinocerebellar ataxia. In our laboratory we offer tests for both known mutations (information about other mutation can be found here: https://www.eurovetgene.com/spinocerebelarna-ataksija-sca). However, there are still some cases of SCA that cannot be explained by either of them.

Inheritance: autosomal recessive - read more

Mutation: KCNJ10 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Price:

52.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
It appears you are using an older browser we don't support fully! For better and user friendly experience use one of the following internet browsers or update your current browser to the latest version.