Thrombopathie - Landseer

Thrombopathia is an inherited platelet disorder. Affecteddogs have abnormal platelet function because they are not able to stick together properly and therefore cannot form a clot. Dogs exhibit typical signs of platelet defects including bleeding from snouts, gingival bleeding,and petechiation. Other symptoms include weakness and rear limb paralysis secondary tospinal cord hemorrhage. The platelet defect is characterized by impairedor absent platelet aggregation responses to all agonistsexcept thrombin; blood coagulation is delayed due to thrombin respond delay occurring in 5-6 minutes instead in 2-3 minutes. Thrombopathia has been reported in different dog breeds including Basset hound, Landseer and American Eskimo dog. Different mutations in genes of all mentioned breeds lead to thrombopathia with similar symptoms.

Inheritance: autosomal recessive - read more

Mutation: RASGRP2 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.

Réduction

(-30,0%)

54,00 €

Prix:

37,80 €

  • Vous pouvez commander un kit d'échantillonnage gratuit.
  • Un seul échantillon est nécessaire pour chaque animal, même si vous commandez plusieurs tests.
  • Nous conservons les échantillons pour vous permettre de commander des tests supplémentaires.
  • Nous proposons l'aide d'experts pour l'interprétation des résultats.
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