Van den Ende-Gupta Syndrome (VDEGS) is a hereditary disease which can be tested with a DNA test. Van den Ende-Gupta Syndrome (VDEGS) is a skeletal syndrome causing severe skeletal anomalies that are already evident in puppies. The disorder is characterised by patellar luxation, underbite (shorter upper jaw), dislocated radial head and deviated nasal septum. In one study, 22% of the control population were carriers of the disorder.
Inheritance: autosomal recessive - read more
Mutation: SCARF2 gene
Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.
Disease control: read more
DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.