Scott Syndrome or haemorrhagic diathesis is a rare autosomal recessive canine disease. It is characterised by deficiency of binding factor X, resulting in lack of procoagulant activity and bleeding abnormalities, with no evidence of skeletal malformation. The disease typically manifests as bruising and haematoma formation after the operation, nontraumatic haemorrhage into joints, soft tissue and epistaxis. The diagnosis is complicated due to normal laboratory test results.

Inheritance: autosomal recessive - read more

Mutation: ANO6 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.