Neonatal Cerebellar Cortical Degeneration (NCCD)

Neonatal Cerebellar Cortical Degeneration (NCCD)is a hereditary disease which can be tested with a DNA test.Neonatal cerebellar cortical degeneration (NCCD) is a neurodegenerative hereditary disease found in several canine breeds including Beagles. NCCD in Beagle is characterised by clinical signs of cerebellar dysfunction, such as ataxia, crossing of legs, uncoordinated movement, loss of balance and tremor of the head and legs. First symptoms appear at around 3 weeks of age when puppies normally develop coordinated movement. The majority of puppies affected with NCCD are euthanized shortly after diagnosing the first signs of this disease.

Inheritance: autosomal recessive - read more

Mutation: SPTBN2 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.


54.00 €

  • You can order free sampling kit.
  • Only one sample is required for each animal, even if you order several tests.
  • Samples are stored for the option to order additional tests.
  • We offer expert assistance in interpreting the results.
Suitable for breeds
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