Ehlers Danlos syndrome is an autosomal recessive disorder of connective tissue that feature painful tissue fragility, skin hyper-extensibility and articular hyper-mobility. The clinical signs include the dog’s hyper-mobile carpal, tarsal and stifle joints and abnormal skin (loose and hyper-elastic with several wounds and large atrophic scars). The affected dogs usually have to be euthanised due to severe injury that can result even from minimal trauma.

Inheritance: autosomal recessive - read more

Mutation: ADAMTS2 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.

Disease control: read more

DNA test sample: EDTA whole blood (1.0 ml) or buccal swabs. Detailed information about sampling can be found here.